“Pegah Khosravi”


IPM Positions

Post-Doctoral Research Fellow, School of Biological Sciences
(2014 - 2017 )

Research Interests

My training in genetics started during the time I worked at ABRII on my master project. My zeal in using mathematical modeling and algorithms for describing different biological systems inspired me to pursue a Ph.D. in Bioinformatics at Department of Bioinformatics, Institute of Biochemistry and Biophysics (IBB), University of Tehran in 2009. I subsequently went on to join the Department of Molecular Systems Biology at ACECR and School of Biological Science at Institute for Research in Fundamental Sciences (IPM), which are leading institutes in the field of Bioinformatics in Iran in 2010. My academic background and interest in Bioinformatics gave me the opportunity to get financial support from the Iranian Ministry of Science scholarship to be a visiting scientist at Donnelly Center for Cellular and Bimolecular Research, University of Toronto, Canada, for a year. This was a great opportunity for me to work in one of the top-notch research groups in the field of Bioinformatics. About my projects, they are based on transcriptome data and try to discover dynamical changes during cancer progression. I analyzed the structural changes in a network during different stages of various cancers ranging from primary tumor to metastasis. I am also trying to develop new algorithms and approaches to detecting critical genes in complex diseases such as cancer. I work well as part of a team as well as on my own. Outside of work, I enjoy hiking, playing the Santour (Dulcimer), cooking and Nard (Backgammon).


Top reading paper at RSG (2015)
Broad Institute of MIT and Harvard travel fellowship (2013)
Iranian Ministry of Science scholarship for student research (2012)

Related Papers

1. M. Habibi and P. Khosravi
Disruption of the Protein Complexes from Weighted Complex Networks
computational biology and bioinformatics DOI: 10.1109/TCBB.2018.2859952 (2018), 1  [abstract]
2. Y. Asgari, P. Khosravi, Z. Zabihinpour and M. Habibi
Exploring candidate biomarkers for lung and prostate cancers using gene expression and flux variability analysis
Integrative Biology (2018), 113-120  [abstract]
3. R. Aghdam, T. Baghfalaki, P. Khosravi and E. Saberi Ansari
The Ability of Different Imputation Methods to Preserve the Significant Genes and Pathways in Cancer
Genomics, proteomics & bioinformatics 15 (2017), 396-404  [abstract]
4. A. Emamjomeh, E. Saboori Robat, J. Zahiri, M. Solouki and P. Khosravi
Gene co-expression network reconstruction: a review on computational methods for inferring functional information from plant-based expression data
Plant Biotechnology Reports (2017), 10.1007/s11816-017-0433-z  [abstract]
5. R. Aghdam, P. Khosravi and E. Saberi Ansari
Comparative Analysis of Gene Regulatory Networks Concepts in Normal and Cancer Groups
Bioinformatics and Biocomputational Research (2016), 1  [abstract]
6. J. Montojo. , P. Khosravi. , V. H. Gazestani. and G. D. Bader.
SIREN Cytoscape plugin: Interaction Type Discrimination in Gene Regulatory Networks
arXiv (2015), arXiv preprint arXiv:1512.05067  [abstract]
7. P. Khosravi. and E. Ebrahimie.
Does the overall shape of gene networks differ between cancer and normal states? Towards a comprehensive understanding of cancer system biology by meta-analysis of various cancer transcriptomes
The RECOMB/ISCB conference on Regulatory and System Genomics with DREAM challenge (2015), 101-102  [abstract]
8. P. Khosravi. , V. H. Gazestani. , B. Law. , G. D. Bader. and M. Sadeghi.
Comparative analysis of co-expression networks reveals molecular changes during the cancer progression
IFMBE 51 (2015), 1481  [abstract]
9. P. Khosravi. , V. H. Gazestani. , L. Pirhaji. , B. Law. , M. Sadeghi. , B. Goliaei. and G. D. Bader.
Inferring interaction type in gene regulatory networks using co-expression data
AMB Vol: 10, DOI: 10.1186/s13015-015-0054-4 (2015), 23  [abstract]
10. P. Khosravi. , V. H. Gazestani. , M. Akbarzadeh. , S. Mirkhalaf. , M. Sadeghi. and B. Goliaei.
Comparative Analysis of Prostate Cancer Gene Regulatory Networks via Hub Type Variation
Avicenna J Med Biotech 7 (2015), 8-15  [abstract]
11. P. Khosravi. , J. Zahiri. , V. H. Gazestani. , S. Mirkhalaf. , M. Akbarzadeh. , M. Sadeghi. and B. Goliaei.
Analysis of Candidate Genes Has Proposed the Role of Y Chromosome in Human Prostate Cancer
Iranian Journal of Cancer Prevention 7 (2014), 204-211  [abstract]
12. P. Khosravi. , V. H. Gazestani. , Y. Asgari. , B. Law. , M. Sadeghi. and B. Goliaei.
Network-based approach reveals Y chromosome influences prostate cancer susceptibility
Computers in Biology and Medicine 54 (2014), 24-31  [abstract]
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