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Paper   IPM / Biological / 13244
School of Biological Sciences
  Title:   An Information Theoritical Approch To Secondary Structure Assignment
1.  M. Habibi.
2.  C. Eslahchi.
3.  H. Pezeshk.
4.  M. Sadeghi.
  Status:   Published
  Journal: Iran. Int. J. Sci.
  No.:  3
  Vol.:  34
  Year:  2008
  Pages:   41-48
  Supported by:  IPM
The automatic assignment of the protein secondary structure from three dimensional coordinates is an essential step in the characterization of protein structure. Although the recognition of secondary structure elements as alpha helices and beta sheets seem straightforward, but there are many different definitions, each regarding different criteria. We introduce new algorithm for the protein secondary structure assignment based on a number of geometric parameters and by using the entropy. A sequence is partitioned to segments. Then the secondary structure elements are assigned to each of these segments. It is shown that if the entropy of a segment increases then the regularity in the structure decreases. So it is concluded that the concept of entropy could be used as a measure of regularity of the secondary structure.

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