“Bulletin Board”

 School of Cognitive Sciences - August 15, 2024

Finding the source of error in working memory in patients with multiple sclerosis (MS)

Researchers at School of Cognitive Sciences (IPM) have found evidences for the source of working memory error in patients with MS. This work has been published in eLife .


Multiple Sclerosis (MS) is an inflammatory disease that mostly affects young adults. Unlike neurodegenerative diseases, the extend of cognitive deficits is not well studied nor well understood.

In a series of papers which the latest one was published in eLife , researchers at Mehdi Sanayei lab at School of Cognitive Sciences at IPM , in collaboration with Iman Adibi at Isfahan University of Medical Sciences, showed that although MS patients have relatively normal function in attention, they suffer from working memory deficits.

Furthermore, through cognitive modeling, they showd that working memory deficit in MS is similar to what was previously observed in Alzheimer’s disease, and not Parkinson's disease. Whether Alzheimer’s and MS might have similarities in their pathophysiology in affecting working memory needs further investigation.

Papers Links:
Multiple Sclerosis and Related Disorders
Scientific Reports
Multiple Sclerosis and Related Disorders
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