We are involved in a large international collaboration which is
studying resistance to trypanosomiasis in African cattle using a
range of genomic and post-genomic strategies (large scale
microarray experiments, quantitative trait loci, congenic mice,
metabolic profiling etc). This work has helped us to understand in
much more detail the mechanisms of resistance and susceptibility
to infection ? and to surprising results around the interface
between lipids and inflammation in controlling immunopathology.
This has now led to interesting comparisons with serious disease
in humans ? and the potential for novel treatments for patients in
intensive care. The talk will also highlight some of the lessons
learnt in developing an integrated computational environment for
handling such diverse and complex data.
Date:||Saturday, May 20, 2006, 16:00-18:00|
|Place: ||Niavaran Bldg., Niavaran Square, Tehran, Iran|