|Thursday 27 July 2017|
|Events for day: Thursday 26 January 2017|
| 10:00 - 11:00 Weekly Seminar|
Accurate Identification of Orthology relations based on Gene Neighborhood Conservation
Farmanieh Building, Ground Floor, class A.
A first step in comparative genomics is the identification of homologous and more specifically orthologous genes. Orthology relations can be used to transfer annotations from one gene (or protein) to another. However, various genomic events---such as duplication, horizontal gene transfer, etc. ---can cause erroneous assignment of orthology relations. Gene neighborhood information can be used to resolve many ambiguities in orthology inference.
We present OrthoGNC, a software and a method for predicting accurate pairwise orthology relations based on gene neighborhood conservation. ...