“School of Biological Sciences”
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| Paper IPM / Biological Sciences / 13203 |
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| Abstract: | |||||
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Assignment of structural domains in complex protein structures is an important task in
bioinformatics researches. As the number of known protein structures grows rapidly,
the need for automatic methods for determining protein domains based on the proteins
tree-dimensional structure becomes more desirable. In this paper, we introduce a new
domain decomposition algorithm which is based on the dominating set of the graph
representation of a protein. To evaluate our method, we compare our results with the
other computational methods on a commonly used benchmark of 55 proteins. It is
shown that the performance of our algorithm is better than the other automatic
methods
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