| | Dr. Mojtaba Madadi Asl, a postdoctoral researcher at the School of Biological Sciences, Institute for
Research in Fundamental Sciences (IPM), has successfully published his review and research article in
the esteemed journal Physics of Life Reviews, which boasts an impact factor of 13.7 from Elsevier. The
article, titled “Entrainment by transcranial alternating current stimulation: Insights from models of
cortical oscillations and dynamical systems theory”, has been officially released.
Neuronal oscillations play a fundamental role in brain functions, and any disruption in these oscillations
can lead to a wide range of neurological disorders. Transcranial electrical stimulation is a non-invasive
method of brain stimulation that can influence neuronal oscillations, thereby improving brain function.
However, the mechanisms by which it affects the neural networks in the brain are not yet fully
understood. In this article, empirical evidence related to these potential mechanisms is discussed in detail,
with a focus on the interaction between external stimulation and an oscillatory system from a dynamical
perspective. Furthermore, the role of theoretical and computational studies in cortical models and their
ability to predict the effects of brain stimulation is comprehensively reviewed and analyzed. Additionally,
the research findings derived from neural modeling in this article suggest that fundamental biophysical
concepts, such as the phase response curve in neurons, can elucidate the diverse effects of electrical
stimulation on neural networks in the brain. Consequently, the development and optimization of brain
stimulation methods, as well as the understanding of their mechanisms of action on neural networks,
necessitate greater convergence between empirical studies and computational modeling.
For more information, please visit the following link:Find more info in this link: https://doi.org/10.1016/j.plrev.2025.03.008
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