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We investigate the statistical isotropy and Gaussianity of temperature fluctuations of Cosmic Microwave Background radiation (CMB) data from {\it Wilkinson Microwave Anisotropy Probe} survey, using the Multifractal Detrended Fluctuation Analysis, Rescaled Range and Scaled Windowed Variance methods. These methods verify that there is no evidence for violation of statistical isotropy in CMB data. The multifractal detrended fluctuation analysis shows that Cosmic Microwave Background fluctuations has a long range correlation function with a multifractal behavior. By comparing our analysis with the artificial shuffled and surrogate series of CMB data, we conclude that the multifractality nature of temperature fluctuation of CMB is mainly due to the long-range correlations and the map is consistent with a Gaussian distribution.
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