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We argue that different aspects of Light-Front QCD at confined phase can be recovered by the Matrix Quantum Mechanics of D0-branes. The concerning Matrix Quantum Mechanics is obtained from dimensional reduction of pure Yang-Mills theory to 0+1 dimension. The aspects of QCD dynamics which are studied in correspondence with D0-branes are: 1) phenomenological inter-quark potentials, 2) whiteness of hadrons and 3) scattering amplitudes. In addition, some other issues such as the large-N behavior, the gravity--gauge theory relation and also a possible justification for involving ``non-commutative coordinates'' in a study of QCD bound-states are discussed.
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