|Wednesday 4 October 2023|
|Events for day: Thursday 28 September 2023|
| 10:00 - 12:30 Weekly Seminar|
Single-cell multi-omics analysis identifies context specific gene regulatory gates and mechanisms
Deciphering tissue- and cell-type specific gene regulatory networks from single-cell RNA sequencing (scRNA-seq) represents an area of active research. While past efforts have focused on reconstructing directed transcription factor (TF) to target gene networks, logic-based models enable interrogation of more complex combinatorial relationships between regulators. In particular, Boolean logic models can capture higher-order TF interactions, represented through AND, OR, and XOR logic gates. We propose a novel approach for inferring TF-gene networks from scRNA-seq while simultaneously elucidating the underlying Boolean logic combining TF activiti ...
11:00 - 12:00 Theory weekly seminar (TWS)
Horizon Strings as 3d Black Hole Microstates
PARTICLES AND ACCELERATORS
We construct microstates of 3d black holes in the Hilbert space of tensionless null strings with non-zero winding along the bifurcation horizon. Counting these string states we recover the Bekenstein-Hawking entropy and its semiclassical logarithmic corrections.
Seminar Room, School of Particles and Accelerators, IPM