| Thursday 16 January 2025 | |
| Events for day: Thursday 09 June 2022 |
| 11:00 - 12:30 Weekly Webinar Memory Deficit in Temporal Lobe Epilepsy School BIOLOGICAL SCIENCES https://www.skyroom.online/ch/arashfj/weekly-seminar-ipm-bio Memory impairment is a common cognitive deficit in temporal lobe epilepsy (TLE). The hippocampus is severely altered in TLE exhibiting multiple anatomical changes that lead to a hyperexcitable network capable of generating frequent epileptic discharges and seizures. In this study we investigated whether hippocampal involvement in epileptic activity drives working memory deficits. We employed the supra-hippocampal kainic acid (KA) mouse model of TLE. We observed a working memory deficit in epileptic mice in a delayed-alternation spatial working memory task. We further ... |