Sunday 4 May 2025 | ![]() |
Events for day: Thursday 04 January 2024 |
10:00 - 12:30 Weekly Seminar Computational comparative genomics at scale School BIOLOGICAL SCIENCES Genome data keeps piling up, with efforts to sequence 1.5 million eukaryotic species, which could transform our understanding of evolution. However, this requires an overhaul of conventional comparative genomics methods limited to studying tens of genomes. Methods for inferring orthologous genes and phylogenetic relationships are computationally demanding. In this talk, I will present FastOMA and Read2Tree which tackle aforementioned challenges. FastOMA is a method for inferring orthology relationships combining k-mer-based placement, species-tree guided subsampling, and highly parallel computing to achieve near-linear performance in the numb ... |