| Monday 23 December 2024 | |
| Events for day: Thursday 10 February 2022 |
| 11:00 - 12:00 Weekly Webinar Phenotype-genotype Correlation in Familial Heart Disease: Left Ventricular Non-compaction School BIOLOGICAL SCIENCES Cardiomyopathies are a group of common heart disorders that affect numerous people worldwide. Left ventricular non-compaction (LVNC) is a structural disorder of the ventricular wall, categorized as a type of cardiomyopathy that mostly caused by genetic disorders . Genetic variations are underlying causes of developmental deformation of the heart wall and the resultant contractile insufficiency. Here, we investigated a family with several affected members exhibiting LVNC phenotype. By whole-exome sequencing (WES) of three affected members, we identified a novel heterozygous missense variant (c.1963C>A: ... 18:00 - 20:00 Commutative Algebra Webinar Cellular Resolutions and Powers of Monomial Ideals School MATHEMATICS Using combinatorial structures to obtain resolutions of monomial ideals is an idea that traces back to Diana Taylor?s thesis, where a simplex associated to the generators of a monomial ideal was used to construct a free resolution of the ideal. This concept has been expanded over the years, with various authors determining conditions under which simplicial or cellular complexes can be associated to monomial ideals in ways that produce a free resolution. In a research project initiated at a BIRS workshop ?Women in Commutative Algebra? in Fall 2019, the authors studied simplicial and cellular structures that produced resolutions of powers ... |