“School of Biological Sciences”
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| Paper IPM / Biological Sciences / 17784 |
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| Abstract: | |||||||||||
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Drug repositioning, the identification of new therapeutic uses for existing drugs, is crucial for accelerating
drug discovery and reducing development costs. Some methods rely on heterogeneous networks, which may not fully
capture the complex relationships between drugs and diseases. However, integrating diverse biological data sources offers
promise for discovering new drug-disease associations (DDAs). Previous evidence indicates that the combination of
information would be conducive to the discovery of new DDAs. However, the challenge lies in effectively integrating
different biological data sources to identify the most effective drugs for a certain disease based on drug-disease coupled
mechanisms.
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