“School of Biological Sciences”
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| Paper IPM / Biological Sciences / 17573 |
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| Abstract: | |||||
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To better understand the dynamics of these changes, we constructed a transcriptional cell atlas of the testis, integrating single-cell RNA sequencing data from over 26,000 cells across five developmental stages: fetal germ cells, infants, childhood, peri-puberty, and adults. We employed various analytical techniques, including clustering, cell type assignments, identification of differentially expressed genes, pseudotime analysis, weighted gene co-expression network analysis, and evaluation of paracrine cellâcell communication, to comprehensively analyze this transcriptional cell atlas of the testis.
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